Butabarbital will lessen the extent or impact of fedratinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Result of coadministering a solid CYP3A4 inducer with fedratinib hasn't been studied. butabarbital will decrease the level or result of estrogens esterified by impacting hepatic/intestinal enzyme CYP3A4 metabolism. https://bille885oua9.sharebyblog.com/profile